The disease is characterized by abnormal deposits of immunoglobulin a an antibody in the blood vessels, leading to their inflammation vasculitis. The inflammation causes blood vessels in the skin, intestines. Henochschonlein purpura childrens hospital of philadelphia. Hsp is characterized by the classic tetrad of rash, abdominal pain, arthritisarthralgia, and glomerulonephritis. Gastroenterology research practice 2010, article id 597648. The small vessels of the skin, joints, kidneys, and digestive organs. The most striking feature of this form of vasculitis is a purplish rash, typically on the lower legs and buttocks. Gastrointestinal manifestations of henoch schonlein purpura. Hypersensitivity vasculitis and henochschonlein purpura. Further investigations may be required if the diagnosis is unclear, abdominal symptoms are severe or where there is evidence of significant renal involvement hypertension, macroscopic haematuria or proteinuria most cases are selflimiting and require only. Hsp is most common in younger pts clinical red maculopapules on. It is not clear what triggers the condition, but it often appears a few weeks after an upper respiratory infection such as strep or mycoplasma. Henochschonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels.
Neurologic manifestations of schonlein henoch purpura. Damage to your blood vessels causes them to swell and bleed. Usually, the immune system makes antibodies, or proteins, to protect the body from foreign substances such as bacteria or viruses. Hsp most commonly affects the blood vessels in your skin, joints, intestines, and kidneys. O seu diagnostico e essencialmente clinico, baseado na presenca de dois ou mais dos. Henochschonlein purpura, sometimes known as hsp, is an autoimmune condition that causes inflammation in the tiny blood vessels of the skin. Please use one of the following formats to cite this article in your essay, paper or report. The role of corticosteroid in hemorrhagic bullous henoch schonlein purpura. Henochschonlein purpura associated with malignancy in adults. Henochschonlein purpura hsp is the most common vasculitis of childhood and affects the small vessels. Nov 16, 2018 please use one of the following formats to cite this article in your essay, paper or report.
Henochschonlein purpura hsp is a form of vasculitis, a condition that involves inflammation of the blood vessels. Henoch schonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. Henoch schonlein purpura hsp is the most common vasculitis of childhood with an incidence of 1418100 000 children per year. With kidney involvement, there may be a loss of small amounts. Henoch schonlein purpura hsp is a disease involving inflammation of small blood vessels. Henoch schonlein purpura hsp is an autoimmune, multisystem, acute vasculitis of childhood commonly involving the skin, gut, joints and the kidneys. Hemorrhagic macules, papules, and urticarial lesions on the foot of a child. It predominantly affects the skin, joints, gastrointestinal. Hsp is the most common form of vasculitis in childhood and affects about 20 in 100,000 children. Gastrointestinal manifestations of henochschonlein purpura. Henochschonlein purpura anaphylactoid purpura, vascular purpura internal medicine an acquired form of small vessel vasculitis with igadominant immune deposits affecting small vesselsarteries, capillaries, venules, typically of the skin, gut, and glomeruli, associated with arthralgia andor arthritis. Henochschonlein purpura also known as iga vasculitis is a disorder that causes the small blood vessels in your skin, joints, intestines, and kidneys to become inflamed and bleed. Severe hemorrhagic bullous lesions in henoch schonlein purpura. Henochschonlein purpura is caused by an abnormal immune system response in which the bodys immune system attacks the bodys own cells and organs.
Henochschonlein purpura hsp is an autoimmune, multisystem, acute vasculitis of childhood commonly involving the skin, gut, joints and the kidneys. It occurs most commonly in children ages 26, although it can occur at any age. Henochschonlein purpura hsp is a condition that causes your immune system to attack and damage your blood vessels. William heberden, a london physician, described the first cases of henoch schonlein purpura hsp in in describing hsp, heberden wrote of a. Hsp is most common in younger pts clinical red maculopapules on legs and buttocks. Henoch schonlein purpura hsp is the most common vasculitis of childhood and affects the small vessels. Jul 24, 2019 henoch schonlein purpura also known as iga vasculitis is a disorder that causes the small blood vessels in your skin, joints, intestines, and kidneys to become inflamed and bleed. Henochschonlein purpura symptoms and causes mayo clinic. Hsp can happen at any age but is most common in children 2 to 11 years of age.
In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin, often with joint pain and abdominal pain. Henochschonlein purpura hsp, also known as iga vasculitis, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. Henochschonlein purpura definition of henochschonlein. Dec 10, 2018 henoch schonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. Its not usually serious, but can sometimes lead to kidney problems. Urinalysis is the only investigation required in a classic presentation of hsp. Henochschonlein purpura symptoms, diagnosis and treatment. Create a free personal account to download free article pdfs, sign up for alerts, customize your interests, and more.
285 568 271 583 708 278 145 836 283 1258 480 1475 178 812 698 514 1496 514 1401 580 961 840 810 362 796 1170 1218 101 333 1140 817